Kcnt2 Antibodies

AND Kcnt2 ELISA kits, Kcnt2 Proteins

Many biological assays use antibodies to detect Kcnt2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kcnt2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kcnt2 antibodies...

We validate the specificity of these antibodies to Kcnt2 by testing them on tissues known to express Kcnt2 positively and negatively. Browse below to find the Kcnt2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Kcnt2 Infographic by Boster Bio

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KCNT2 (NM_198503) Human Over-expression Lysate

Human

$960
Cat # LS343450
20 µg, 100 µg

Kcnt2 Overview

Facts about Potassium channel subfamily T member 2.

Potassium channel subfamily T member 2 (Kcnt2)

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents.

Activated by large intracellular sodium and chloride levels (PubMed:14684870, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:17699666).

Gene Information

Rat
Gene Name:	Kcnt2
Uniprot:	Q6UVM4
Entrez:	304827

Family

Belongs to:

potassium channel family

Alternative Names

KCa4.2; MGC119610; MGC119611; MGC119612; potassium channel subfamily T member 2; potassium channel, subfamily T, member 2; Sequence like an intermediate conductance potassium channel subunit; SLICKMGC119613; SLO2.1; sodium activated potassium channel; sodium and chloride activated ATP sensitive potassium channel; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1; sodium- and chloride-activated ATP-sensitive potassium channel; sodium-and chloride-activated ATP-sensitive potassium channel (SLICK)

Molecular Weight

Mass (kDA):
131.1 kDA

Genomic Context


Rat

Location:	13q21
Sequence:	13;

Tissue Specificity

Detected in brain, and at low levels in heart. Detected in brainstem, including auditory neurons such as the medial nucleus of the trapezoid body. Detected in the olfactory bulb, red nucleus, facial nucleus, pontine nucleus, oculomotor nucleus, substantia nigra, deep cerebellar nuclei, vestibular nucleus, and the thalamus. Detected in hippocampal CA1, CA2, and CA3 regions, the dentate gyrus, supraoptic nucleus, hypothalamus, dorsal root ganglion, and cortical layers II, III, and V. Detected in striatum cholinergic interneurons.

Diseases

Retinoblastoma
Persistent Hyperinsulinemia Hypoglycemia Of Infancy
Chimera Disorder
Hypoxia
Hyperinsulinism

Pathways

Secretion
Transport
Insulin Secretion

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Kcnt2

References

PMID: 14684870 by Bhattacharjee A., et al. Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP.

PMID: 15717307 by Bhattacharjee A., et al. Localization of the Na+-activated K+ channel Slick in the rat central nervous system.