KCTD12 Antibodies

AND KCTD12 ELISA kits, KCTD12 Proteins

Many biological assays use antibodies to detect KCTD12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCTD12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCTD12 antibodies...

We validate the specificity of these antibodies to KCTD12 by testing them on tissues known to express KCTD12 positively and negatively. Browse below to find the KCTD12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCTD12 Infographic by Boster Bio

All KCTD12 Products

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Anti-KCTD12 Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$370
Cat # A07946-1
100 μl/vial

KCTD12 Overview

Facts about BTB/POZ domain-containing protein KCTD12.

KCTD12 3D structure. Source: alphafold

BTB/POZ domain-containing protein KCTD12 (KCTD12)

Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly change the G-protein signaling of these receptors by accelerating onset and promoting desensitization (By similarity).

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Gene Information

Human
Gene Name:	KCTD12
Uniprot:	Q96CX2
Entrez:	115207

Family

Belongs to:

No superfamily

Alternative Names

BTB/POZ domain-containing protein KCTD12; C13orf2; chromosome 13 open reading frame 2; FLJ33073; KIAA1778PFET1PFETIN; Pfetin; potassium channel tetramerisation domain containing 12; Predominantly fetal expressed T1 domain

Molecular Weight

Mass (kDA):
35.701 kDA

Genomic Context


Human

Location:	13q22.3
Sequence:	13; NC_000013.11 (76880175..76886405, complement)

Subcellular Localizations

Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane.

Diseases

Gastrointestinal Stromal Tumors
Neoplasms
Neoplasm Metastasis
Stromal Neoplasm
Hearing Problem
Leiomyosarcoma
Synovial Sarcoma
Malignant Paraganglionic Neoplasm
Bone Neoplasms
Diabetes Mellitus
Myxoid Cyst
Sarcoma

Diabetes Mellitus, Non-insulin-dependent
Osteosarcoma
Malignant Peripheral Nerve Sheath Tumor
Malignant Neoplasms
Nervousness
Malignant Fibrous Histiocytoma
Sarcoma, Clear Cell

Pathways

Glucose Homeostasis
Insulin Secretion
Brain Development
Localization
Secretion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCTD12

References

PMID: 15357420 by Resendes B.L., et al. Isolation from cochlea of a novel human intronless gene with predominant fetal expression.

PMID: 20400944 by Schwenk J., et al. Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits.