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- Table of Contents
Designing an IHC experiment for KDELR3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the KDELR3 IHC Guide1 Citations
Facts about ER lumen protein-retaining receptor 3.
Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity).
| Human | |
|---|---|
| Gene Name: | KDELR3 |
| Uniprot: | O43731 |
| Entrez: | 11015 |

| Belongs to: |
|---|
| ERD2 family |

ER lumen protein retaining receptor 3; ERD2L3; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3
Mass (kDA):
25.027 kDA

| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (38468062..38483447) |
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.




PMID: 12529303 by Collins J.E., et al. Reevaluating human gene annotation: a second-generation analysis of chromosome 22.
PMID: 18086916 by Raykhel I., et al. A molecular specificity code for the three mammalian KDEL receptors.