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- Table of Contents
Facts about Kelch-like protein 24.
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| Human | |
|---|---|
| Gene Name: | KLHL24 |
| Uniprot: | Q6TFL4 |
| Entrez: | 54800 |

| Belongs to: |
|---|
| No superfamily |

DRE1; EAA4; GLR6; GluK2; GLUK6; GluR6; Kainate Receptor Interacting Protein For GluR6; Kainate Receptor-Interacting Protein For GluR6; Kelch-Like 24 (Drosophila); Kelch-Like 24; Kelch-Like Family Member 24; Kelch-Like Protein 24; KLHL24 ; KRIP6; MRT6; Protein DRE1
Mass (kDA):
68.361 kDA

| Human | |
|---|---|
| Location: | 3q27.1 |
| Sequence: | 3; NC_000003.12 (183635619..183684519) |
Expressed in the skin (PubMed:27889062, PubMed:27798626). Found in keratinocytes, dermal fibroblasts, and melanocytes (PubMed:27889062). Basal-layer keratinocytes have lower KLHL24 expression than suprabasal keratinocytes (PubMed:27798626).
Perikaryon. Cell projection, axon. Cytoplasm. Cell junction, desmosome. Cell junction, adherens junction.




PMID: 27889062 by He Y., et al. Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility.
PMID: 27798626 by Lin Z., et al. Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility.