Kelch-like protein 42 Antibodies

AND KLHL42 ELISA kits, Kelch-like protein 42 Proteins

Many biological assays use antibodies to detect Kelch-like protein 42, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kelch-like protein 42 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kelch-like protein 42 antibodies...

We validate the specificity of these antibodies to Kelch-like protein 42 by testing them on tissues known to express KLHL42 positively and negatively. Browse below to find the KLHL42 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLHL42 Infographic by Boster Bio

All KLHL42 Products

Product

Figures

Specificity

Applications

Price

Anti-KLDC5 KLHL42 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A14008
100ul

KLHDC5 (KLHL42) (NM_020782) Human Recombinant Protein

$1249
Cat # PROTQ9P2K6
20 µg

KLHDC5 (KLHL42) (NM_020782) Human Over-expression Lysate

Human

$628
Cat # LS057542
100 µg

KLHL42 Overview

Facts about Kelch-like protein 42.

KLHL42 3D structure. Source: alphafold

Kelch-like protein 42 (KLHL42)

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1.

Involved in microtubule dynamics during mitosis. .

Gene Information

Human
Gene Name:	KLHL42
Uniprot:	Q9P2K6
Entrez:	57542

Family

Belongs to:

No superfamily

Alternative Names

Kelch-like protein 42

Molecular Weight

Mass (kDA):
56.868 kDA

Genomic Context


Human

Location:	12p11.22
Sequence:	12; NC_000012.12 (27780233..27803040)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, spindle. Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.

Interacting Proteins

CALCOCO2
DDI1
FAM168A
SERTAD1
SSX2IP

STAM2
TRIM23
UBQLN1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLHL42

References

PMID: 19261606 by Cummings C.M., et al. The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells.