Kelch-like protein 9 Antibodies

AND KLHL9 ELISA kits, Kelch-like protein 9 Proteins

Many biological assays use antibodies to detect Kelch-like protein 9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kelch-like protein 9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kelch-like protein 9 antibodies...

We validate the specificity of these antibodies to Kelch-like protein 9 by testing them on tissues known to express KLHL9 positively and negatively. Browse below to find the KLHL9 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLHL9 Infographic by Boster Bio

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Anti-Kelch-like protein 9 KLHL9 Antibody

Western blot analysis of extracts of 293T cells, using KLHL9 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded rat ovary using KLHL9 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat heart using KLHL9 antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A13280
100ul

KLHL9 Overview

Facts about Kelch-like protein 9.

KLHL9 3D structure. Source: alphafold

Kelch-like protein 9 (KLHL9)

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.

Gene Information

Human
Gene Name:	KLHL9
Uniprot:	Q9P2J3
Entrez:	55958

Family

Belongs to:

No superfamily

Alternative Names

FLJ13568; FLJ21815; kelch-like 9 (Drosophila); kelch-like protein 9; KIAA1354

Molecular Weight

Mass (kDA):
69.429 kDA

Genomic Context


Human

Location:	9p21.3
Sequence:	9; NC_000009.12 (21329665..21335404, complement)

Diseases

Hereditary Melanoma
Cutaneous Melanoma
Melanoma
Malignant Paraganglionic Neoplasm
Aneuploidy

Pathways

Mitosis
Anaphase
Cytokinesis
Cell Cycle
Proteolysis
Spindle Assembly Checkpoint
Metaphase

Chromosome Segregation
Spindle Assembly

PTMs

Ubiquitination

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLHL9

References

PMID: 14528312 by Furukawa M., et al. Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.

PMID: 17543862 by Sumara I., et al. A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.