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Killin Antibodies

AND KLLN ELISA kits, Killin Proteins

Many biological assays use antibodies to detect Killin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Killin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Killin antibodies...

We validate the specificity of these antibodies to Killin by testing them on tissues known to express KLLN positively and negatively. Browse below to find the KLLN antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLLN Infographic by Boster Bio

KLLN protein infographic

All KLLN Products

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KLLN (NM_001126049) Human Over-expression Lysate

KLLN Human Over-expression Lysates NM_001126049

KLLN Human Over-expression Lysates NM_001126049

Human

$628
Cat # LS100144748
20 µg, 100 µg

KLLN Overview

Facts about Killin.

KLLN 3D structure

KLLN 3D structure. Source: alphafold

Killin (KLLN)

DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Being able to inhibit DNA synthesis and S phase arrest combined to apoptosis.

Has affinity to both dual - and single- stranded DNA. .

Gene Information

Human
Gene Name:	KLLN
Uniprot:	B2CW77
Entrez:	100144748

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

CWS4; KILLIN; Killin, P53-Regulated DNA Replication Inhibitor

Molecular Weight

Mass (kDA):
19.958 kDA

Molecular Weight

Genomic Context


Human

Location:	10q23.31
Sequence:	10; NC_000010.11 (87859161..87863437, complement)

Subcellular Localizations

Nucleus.

Subcellular Localization

Diseases

Malignant Neoplasms
Hamartoma Syndrome, Multiple
Neoplasms
Adenocarcinoma
Follicular Thyroid Carcinoma
Mutation, Out-of-frame
Malignant Neoplasm Of Breast
Glioma
Thyroid Neoplasm

Papillary Thyroid Carcinoma
Mammary Neoplasms
Sporadic Breast Carcinoma
Malignant Neoplasm Of Thyroid

Disease

Pathways

Methylation

Pathways

PTMs

Methylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLLN

References

PMID: 18385383 by Cho Y.J., et al. Killin is a p53-regulated nuclear inhibitor of DNA synthesis.

PMID: 21177507 by Bennett K.L., et al. Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.