KLRG1 Antibodies

AND KLRG1 ELISA kits, KLRG1 Proteins

Many biological assays use antibodies to detect KLRG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KLRG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KLRG1 antibodies...

We validate the specificity of these antibodies to KLRG1 by testing them on tissues known to express KLRG1 positively and negatively. Browse below to find the KLRG1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLRG1 Infographic by Boster Bio

All KLRG1 Products

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Product

Figures

Specificity

Applications

Price

Human KLRG1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTQ96E93
Starting from 10ug

Anti-KLRG1 Rabbit Monoclonal Antibody

Western blot analysis of KLRG1 using anti-KLRG1 antibody (M02084)

Human, Mouse, Rat

$370
Cat # M02084
100 μl/vial

KLRG1 (NM_005810) Human Over-expression Lysate

Human

$628
Cat # LS010219
20 µg, 100 µg

KLRG1 Overview

Facts about Killer cell lectin-like receptor subfamily G member 1.

KLRG1 3D structure. Source: alphafold

Killer cell lectin-like receptor subfamily G member 1 (KLRG1)

Plays an inhibitory function on natural killer (NK) cells and T-cell works upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, allowing it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

Gene Information

Human
Gene Name:	KLRG1
Uniprot:	Q96E93
Entrez:	10219

Family

Belongs to:

No superfamily

Alternative Names

2F1; CLEC15A; CLEC15AMAFA-LIKE; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; KLRG1; MAFA; MAFAL; MAFA-L; MAFA-like receptor; MAFAMAFA-2F1; mast cell function-associated antigen (ITIM-containing); Mast cell function-associated antigen; MGC13600

Molecular Weight

Mass (kDA):
21.831 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (8950044..9215657)

Tissue Specificity

Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.

Diseases

Infective Disorder
Virus Diseases
Tissue Adhesions
Neoplasms
Cytomegalovirus Infections
Lymphocytic Choriomeningitis
Inflammation
Listeriosis
Influenza
Exhaustion
Malignant Neoplasms
Vaccinia
Diabetes Mellitus

Vesicular Stomatitis
Carcinoma
Bacterial Infections
Diabetes Mellitus, Non-insulin-dependent
Stomatitis
Acute Infectious Disease
Hiv Infections

Interacting Proteins

LEPROTL1
SYNE4

Pathways

Secretion
Immune Response
Senescence
Cell Differentiation
Cytokine Production
Cell Activation
Aging
Insulin Secretion
Localization
Cell Division
Cell Proliferation
T Cell Differentiation
Cell-cell Adhesion

Replicative Senescence
Cell Death
Cell Adhesion
T Cell Activation
Cell Maturation
Cytolysis
Pathogenesis

PTMs

Phosphorylation

Glycosylation

Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLRG1

References

PMID: 9765598 by Lamers M.B.A.C., et al. Human MAFA has alternatively spliced variants.

PMID: 9842918 by Butcher S., et al. MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells.