KRT75 Antibodies

AND KRT75 ELISA kits, KRT75 Proteins

Many biological assays use antibodies to detect KRT75, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT75 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT75 antibodies...

We validate the specificity of these antibodies to KRT75 by testing them on tissues known to express KRT75 positively and negatively. Browse below to find the KRT75 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KRT75 Infographic by Boster Bio

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KRT75 (NM_004693) Human Over-expression Lysate

Human

$960
Cat # LS009119
20 µg, 100 µg

KRT75 Overview

Facts about Keratin, type II cytoskeletal 75.

KRT75 3D structure. Source: alphafold

Keratin, type II cytoskeletal 75 (KRT75)

Plays a central role in nail and hair formation. Essential part of keratin intermediate filaments in the companion layer of the hair follicle.

Gene Information

Human
Gene Name:	KRT75
Uniprot:	O95678
Entrez:	9119

Family

Belongs to:

intermediate filament family

Alternative Names

CK-75; cytokeratin-75; hK6hf; K6HFcytokeratin type II; K75; KB18; keratin 75; keratin, type II cytoskeletal 75; Keratin-6 hair follicle; keratin-75; PFB; type II keratin-18; Type II keratin-K6hf; Type-II keratin Kb18

Molecular Weight

Mass (kDA):
59.56 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (52424070..52434371, complement)

Tissue Specificity

Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).

Diseases

Disease Of Adrenal Medulla
Pachyonychia Congenita
Thickened Nails

Interacting Proteins

KRT34
NFKBID
WHAMMP3

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT75

References

PMID: 9856802 by Winter H., et al. A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle.

PMID: 10692104 by Rogers M.A., et al. Characterization of a 300 kbp region of human DNA containing the type II hair keratin.