KRTAP12-3 Antibodies

AND KRTAP12-3 ELISA kits, KRTAP12-3 Proteins

Many biological assays use antibodies to detect KRTAP12-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRTAP12-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRTAP12-3 antibodies...

We validate the specificity of these antibodies to KRTAP12-3 by testing them on tissues known to express KRTAP12-3 positively and negatively. Browse below to find the KRTAP12-3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KRTAP12-3 Infographic by Boster Bio

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KRTAP12-3 (NM_198697) Human Over-expression Lysate

Human

$628
Cat # LS386683
20 µg, 100 µg

KRTAP12-3 Overview

Facts about Keratin-associated protein 12-3.

KRTAP12-3 3D structure. Source: alphafold

Keratin-associated protein 12-3 (KRTAP12-3)

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.

Gene Information

Human
Gene Name:	KRTAP12-3
Uniprot:	P60328
Entrez:	386683

Family

Belongs to:

KRTAP type 12 family

Alternative Names

Keratin-associated protein 12-3

Molecular Weight

Mass (kDA):
9.947 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (44657932..44658341)

Tissue Specificity

Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.

Interacting Proteins

CATSPER1
HOXA1
KPRP
KRTAP12-1
LCE1A

LCE1F
LCE2B
LCE3A
LCE3C
LCE4A

OTX1
POU4F2
VASN

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRTAP12-3

References

PMID: 15028290 by Shibuya K., et al. A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.

PMID: 14962103 by Rogers M.A., et al. Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.