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- Table of Contents
KSR1 Antibodies
AND KSR1 ELISA kits, KSR1 Proteins
Many biological assays use antibodies to detect KSR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KSR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KSR1 antibodies...
Designing a Western blot for KSR1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KSR1 Western Blot GuideKSR1 Infographic by Boster Bio
All KSR1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03285
100 μl
Cat # M03285
100 μl
Human, Mouse
ELISA
$540
Cat # EKC1989
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1989
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1333
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1333
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2459
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2459
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2458
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2458
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2457
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2457
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2456
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2456
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2161
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2161
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2160
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2160
1 kit, containing two 96-well plates and all necessary reagents
KSR1 Overview
Facts about Kinase suppressor of Ras 1.
Kinase suppressor of Ras 1 (KSR1)
Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases.
Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity alone.
Gene Information
| Human | |
|---|---|
| Gene Name: | KSR1 |
| Uniprot: | Q8IVT5 |
| Entrez: | 8844 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
kinase suppressor of ras 1; kinase suppressor of ras; KSRRSU2
Molecular Weight
Mass (kDA):
102.16 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q11.2 |
| Sequence: | 17; NC_000017.11 (27456441..27626438) |
Subcellular Localizations
Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cell projection, ruffle membrane. Endoplasmic reticulum membrane. In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Inflammatory Bowel Diseases
- Non-small Cell Lung Carcinoma
- Metaplastic Cell Transformation
- Inflammation
- Malignant Neoplasm Of Pancreas
- Obesity
- Neoplasm Metastasis
Interacting Proteins
- MAP2K2
- VRK2
Pathways
- Localization
- Cell Cycle
- Signal Transmission
- Mapk Cascade
- Cell Migration
- Cell Differentiation
- Cell Proliferation
- Cytokine Production
- Cell Growth
- Rna Interference
- Cell Adhesion
- Hypersensitivity
- Oxidative Phosphorylation
PTMs
- Phosphorylation
- Dephosphorylation
- Phosphorothioation
Research Areas
- Protein Kinase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KSR1
bosterbio.com/bosterbio-gene-info-cards/KSR1
References
PMID: 8521512 by Therrien M., et al. KSR, a novel protein kinase required for RAS signal transduction.
PMID: 10409742 by Stewart S., et al. Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.