Klre1 Antibodies

AND Klre1 ELISA kits, Klre1 Proteins

Many biological assays use antibodies to detect Klre1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Klre1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Klre1 antibodies...

We validate the specificity of these antibodies to Klre1 by testing them on tissues known to express Klre1 positively and negatively. Browse below to find the Klre1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Klre1 Infographic by Boster Bio

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Klre1 Overview

Facts about Killer cell lectin-like receptor subfamily E member 1.

Klre1 3D structure. Source: alphafold

Killer cell lectin-like receptor subfamily E member 1 (Klre1)

Lectin-like receptor for natural killer (NK) cells (PubMed:14707119, PubMed:15069013, PubMed:18713988). Can either inhibit or activate NK cell cytotoxic activity, based on its binding partner (PubMed:14707119, PubMed:15069013, PubMed:18713988).

Heterodimer formation with KLRI1 mediates NK cell inhibition whereas heterodimer formation with KLRI2 mediates NK cell activation (PubMed:18713988). Plays a role in allogeneic recognition by the immune system (PubMed:14707119, PubMed:15069013).

Gene Information

Mouse
Gene Name:	Klre1
Uniprot:	Q8CJC7
Entrez:	243655

Family

Belongs to:

No superfamily

Alternative Names

Klre1; Klre-1; NKG2I

Molecular Weight

Mass (kDA):
26.265 kDA

Genomic Context


Mouse

Location:	6\|6 F3
Sequence:	6;

Tissue Specificity

Expressed in natural killer (NK) cells (at protein level) (PubMed:12782717, PubMed:14707119, PubMed:12715246). Also detected in natural killer T (NKT) cells (at protein level) (PubMed:14707119, PubMed:12715246). Has little or no expression in T cells (at protein level) (PubMed:14707119, PubMed:12715246).

Diseases

Neoplasms
Leukemia
Cytomegalovirus Infections
Hiv Infections
Virus Diseases
Malignant Neoplasms
Lymphoma
Melanoma
Infective Disorder
Tissue Adhesions
Graft-vs-host Disease
Autoimmunity
Immunologic Deficiency Syndromes

Lymphoproliferative Disorders
Hepatitis
Carcinoma
Immunologic Tolerance
Autoimmune Reaction
Malignant Paraganglionic Neoplasm
Arthritis

Pathways

Cell Activation
Immune Response
Cytokine Production
Secretion
Cytolysis
Cell Development
Pathogenesis
T Cell Activation
Cell Proliferation
Cell Recognition
Killer Activity
T Cell Proliferation
Cell Maturation

Chemotaxis
Cell Differentiation
Innate Immune Response
Cell Killing
Localization
Cell Death
Transport

PTMs

Phosphorylation
Biotinylation

Glycosylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Klre1

References

PMID: 12782717 by Westgaard I.H., et al. The lectin-like receptor KLRE1 inhibits natural killer cell cytotoxicity.

PMID: 14707119 by Koike J., et al. Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I.