L2HGDH Antibodies

AND L2HGDH ELISA kits, L2HGDH Proteins

Many biological assays use antibodies to detect L2HGDH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with L2HGDH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop L2HGDH antibodies...

We validate the specificity of these antibodies to L2HGDH by testing them on tissues known to express L2HGDH positively and negatively. Browse below to find the L2HGDH antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: DHDDS

L2HGDH Infographic by Boster Bio

All L2HGDH Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-L2HGDH Antibody

Western blot analysis of extracts of various cell lines, using L2HGDH antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A06150
100ul

L2HGDH (NM_024884) Human Recombinant Protein

Coomassie blue staining of purified L2HGDH protein

$1249
Cat # PROTQ9H9P8
20 µg

Anti-Fruit fly L2HGDH Antibody

Fruit fly

$470
Cat # DZ41224
200 μl/vial

L2HGDH (NM_024884) Human Over-expression Lysate

Human

$960
Cat # LS079944
20 µg, 100 µg

Anti-L2HGDH Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # A06150-1
100 μl/vial

L2HGDH Overview

Facts about L-2-hydroxyglutarate dehydrogenase, mitochondrial.

L2HGDH 3D structure. Source: alphafold

L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH)

Gene Information

Human
Gene Name:	L2HGDH
Uniprot:	Q9H9P8
Entrez:	79944

Family

Belongs to:

L2HGDH family

Alternative Names

2-hydroxyglutarate dehydrogenase; alpha-ketoglutarate reductase; C14orf160alpha-hydroxyglutarate oxidoreductase; chromosome 14 open reading frame 160; DURANIN; EC 1.1.99.2; FLJ12618; L-2-hydroxyglutarate dehydrogenase; L-2-hydroxyglutarate dehydrogenase, mitochondrial; L-alpha-hydroxyglutarate dehydrogenase

Molecular Weight

Mass (kDA):
50.316 kDA

Genomic Context


Human

Location:	14q21.3
Sequence:	14; NC_000014.9 (50242434..50312229, complement)

Tissue Specificity

Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.

Subcellular Localizations

Mitochondrion.

Diseases

Combined D-2- And L-2-hydroxyglutaric Aciduria
Brain Diseases, Metabolic, Inborn
Ataxia
Epilepsy
Metabolic Diseases
Inborn Errors Of Metabolism
Dog Diseases
Brain Neoplasms
Macrocephaly
Cerebellar Ataxia
Subcortical Leukoencephalopathy

Movement Disorders
Neoplasms
Brain Diseases, Metabolic
Leukoencephalopathies
Nerve Degeneration
Glioblastoma

Pathways

Translation
Pathogenesis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/L2HGDH

References

PMID: 15548604 by Rzem R., et al. A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria.

PMID: 16005139 by Rzem R., et al. The gene mutated in L-2-hydroxyglutaric aciduria encodes L-2- hydroxyglutarate dehydrogenase.