Las1l Antibodies

AND Las1l ELISA kits, Las1l Proteins

Many biological assays use antibodies to detect Las1l, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Las1l in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Las1l antibodies...

We validate the specificity of these antibodies to Las1l by testing them on tissues known to express Las1l positively and negatively. Browse below to find the Las1l antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Las1l Infographic by Boster Bio

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Anti-LAS1L Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A08263-1
100 μl/vial

Las1l Overview

Facts about Ribosomal biogenesis protein LAS1L.

Ribosomal biogenesis protein LAS1L (Las1l)

Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA (By similarity).

Functions as a part of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. .

Gene Information

Mouse
Gene Name:	Las1l
Uniprot:	A2BE28
Entrez:	76130

Family

Belongs to:

LAS1 family

Alternative Names

dJ475B7.2; FLJ12525; FLJ30133; FLJ45274; LAS1-like (S. cerevisiae); protein LAS1 homolog

Molecular Weight

Mass (kDA):
89.414 kDA

Genomic Context


Mouse

Location:	X\|X C3
Sequence:	X;

Diseases

Malignant Neoplasms
Neoplasms
Adenocarcinoma
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Pancreatic Ductal Adenocarcinoma
Multiple Malignancy
Aneuploidy
Carcinogenesis
Carcinoma, Pancreatic Ductal

Prostatic Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Ductal Breast Carcinoma

Pathways

Ribosome Biogenesis
Cell Proliferation
Cell Growth
Methylation
Histone H3 Acetylation
Rna Processing
Localization
Rna Interference

Rrna Processing
Nuclear Export
Chromatin Remodeling

PTMs

Sumoylation

Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Las1l

References

PMID: 22872859 by Fanis P., et al. Five friends of methylated chromatin target of protein-arginine- methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.