LCOR Antibodies

AND LCOR ELISA kits, LCOR Proteins

Many biological assays use antibodies to detect LCOR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LCOR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LCOR antibodies...

We validate the specificity of these antibodies to LCOR by testing them on tissues known to express LCOR positively and negatively. Browse below to find the LCOR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LCOR Infographic by Boster Bio

All LCOR Products

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Figures

Specificity

Applications

Price

Anti-LCOR Mouse Monoclonal Antibody [Clone ID: OTI2F8]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LCOR (Right lane) cDNA for 48 hrs and lysed

Human, Mouse

$523
Cat # M08847
100 µl

LCOR (NM_032440) Human Over-expression Lysate

LCOR Human Over-expression Lysates NM_001170765

Human

$960
Cat # LS084458
20 µg, 100 µg

Anti-LCOR Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A08847-1
100 μl/vial

LCOR Overview

Facts about Ligand-dependent corepressor.

LCOR 3D structure. Source: alphafold

Ligand-dependent corepressor (LCOR)

May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors.

Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR. .

Gene Information

Human
Gene Name:	LCOR
Uniprot:	Q96JN0
Entrez:	84458

Family

Belongs to:

No superfamily

Alternative Names

FLJ38026; KIAA1795RP11-175O19.1; LCoR; ligand dependent nuclear receptor corepressor; Mblk1-related protein 2; MLR2; MLR2ligand-dependent corepressor

Molecular Weight

Mass (kDA):
47.007 kDA

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (96832298..96995956)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Carcinoma
Neoplasms
Nervousness
Malignant Neoplasm Of Prostate
Colonic Neoplasms
Malignant Tumor Of Colon
Lung Diseases
Ileus
Carcinogenesis
Leukemia, Myelocytic, Acute
Lung Diseases, Obstructive

Chronic Obstructive Airway Disease
Motor Neuron Disease
Wound Infection
Hemorrhage
Myeloid Leukemia
Pulmonary Emphysema
Acute Promyelocytic Leukemia

Interacting Proteins

CTBP2
GOLGA2
TRAF1

Pathways

Lipid Homeostasis
Cell Differentiation
Histone Acetylation

PTMs

Isopeptide bond
Methylation

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LCOR

References

PMID: 12535528 by Fernandes I., et al. Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms.

PMID: 12700765 by Shi Y., et al. Coordinated histone modifications mediated by a CtBP co-repressor complex.