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- Table of Contents
Facts about Leucine-rich repeat LGI family member 3.
.
| Human | |
|---|---|
| Gene Name: | LGI3 |
| Uniprot: | Q8N145 |
| Entrez: | 203190 |

| Belongs to: |
|---|
| No superfamily |

Leucine-rich glioma-inactivated protein 3; leucine-rich repeat LGI family member 3; leucine-rich repeat LGI family, member 3; LGI1-like protein 4; LGI3; LGIL4
Mass (kDA):
61.704 kDA

| Human | |
|---|---|
| Location: | 8p21.3 |
| Sequence: | 8; NC_000008.11 (22146830..22156806, complement) |
Widely expressed, with highest levels in brain and lung.
Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, synaptosome. Found in the synaptosomal membrane fraction.




PMID: 12023020 by Gu W., et al. The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins.
PMID: 12095917 by Scheel H., et al. A common protein interaction domain links two recently identified epilepsy genes.