Leiomodin-1 Antibodies

AND LMOD1 ELISA kits, Leiomodin-1 Proteins

Many biological assays use antibodies to detect Leiomodin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Leiomodin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Leiomodin-1 antibodies...

We validate the specificity of these antibodies to Leiomodin-1 by testing them on tissues known to express LMOD1 positively and negatively. Browse below to find the LMOD1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Leiomodin-1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LMOD1 IHC Guide

LMOD1 Infographic by Boster Bio

All LMOD1 Products

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Product

Figures

Specificity

Applications

Price

LMOD1 (NM_012134) Human Over-expression Lysate

Human

$628
Cat # LS025802
20 µg, 100 µg

Anti-Leiomodin-1 LMOD1 Antibody

Human

IHC, WB

$405
Cat # A08666
100ul

LMOD1 Overview

Facts about Leiomodin-1.

LMOD1 3D structure. Source: alphafold

Leiomodin-1 (LMOD1)

Mediates nucleation of actin filaments. .

Gene Information

Human
Gene Name:	LMOD1
Uniprot:	P29536
Entrez:	25802

Family

Belongs to:

tropomodulin family

Alternative Names

64 kDa autoantigen 1D; 64 kDa autoantigen 1D3,1D; 64 kDa autoantigen D1,64kD; D1; FLJ55689; leimodin 1 (smooth muscle); leiomodin 1 (smooth muscle); Leiomodin, muscle form; leiomodin-1; SM-LMOD; Smooth muscle leiomodin; thyroid and eye muscle autoantigen D1 (64kD); Thyroid-associated ophthalmopathy autoantigen

Molecular Weight

Mass (kDA):
67.03 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (201896456..201946548, complement)

Tissue Specificity

Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603).

Subcellular Localizations

Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Colocalizes with actin filaments in sarcomeres.

Diseases

Thyroid Associated Opthalmopathies
Graves Disease
Autoimmune Reaction
Disorder Of Eye
Malignant Neoplasms
Autoimmune Diseases
Autoimmunity
Salivary Gland Neoplasms
Tumor Progression
Thyroid Diseases
Carcinoma
Carcinogenesis

Neoplasms
Thyrotoxicosis
Colorectal Cancer
Endocrine Exopthalmos
Invasive Malignant Neoplasm
Hypertrophic Cardiomyopathy
Malignant Paraganglionic Neoplasm

Pathways

Pathogenesis
Sensitization
Ear Development
Cell Differentiation
Hair Cell Differentiation
Inner Ear Development
Localization

Rna Interference

PTMs

Phosphoprotein

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMOD1

References

PMID: 2026759 by Dong Q., et al. Cloning and sequencing of a novel 64-kDa autoantigen recognized by patients with autoimmune thyroid disease.

PMID: 11318603 by Conley C.A., et al. Leiomodins: larger members of the tropomodulin (Tmod) gene family.