Lrguk Antibodies

AND Lrguk ELISA kits, Lrguk Proteins

Many biological assays use antibodies to detect Lrguk, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lrguk in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lrguk antibodies...

We validate the specificity of these antibodies to Lrguk by testing them on tissues known to express Lrguk positively and negatively. Browse below to find the Lrguk antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lrguk Infographic by Boster Bio

All Lrguk Products

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LRGUK (NM_144648) Human Over-expression Lysate

Human

$628
Cat # LS136332
20 µg, 100 µg

Anti-LRGUK Antibody Picoband®

Western blot analysis of LRGUK using anti-LRGUK antibody (A15162-1)

Flow Cytometry analysis of SH-SY5Y cells using anti-LRGUK antibody (A15162-1)

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A15162-1
100 μg/vial

Lrguk Overview

Facts about Leucine-rich repeat and guanylate kinase domain-containing protein.

Leucine-rich repeat and guanylate kinase domain-containing protein (Lrguk)

Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early areas of axoneme development (PubMed:25781171). Not vital for primary cilium biogenesis (PubMed:28003339).

Gene Information

Mouse
Gene Name:	Lrguk
Uniprot:	Q9D5S7
Entrez:	74354

Family

Belongs to:

No superfamily

Alternative Names

FLJ32786; leucine-rich repeat and guanylate kinase domain-containing protein; leucine-rich repeats and guanylate kinase domain containing

Molecular Weight

Mass (kDA):
93.19 kDA

Genomic Context


Mouse

Location:	6\|6 A3.3
Sequence:	6;

Tissue Specificity

Highly expressed in the testis (PubMed:25781171). During spermatid development is initially localised to a supra-nuclear region of round spermatids, and is particularly evident at the leading edge of the developing acrosome and acroplaxome. As maturation proceeded and nuclear elongation initiated, LRGUK moves distally to ultimately reside on the microtubules of the manchette. LRGUK is also evident in the sperm basal body and the sperm tail (PubMed:25781171).

Diseases

Diabetes Mellitus, Non-insulin-dependent
Metabolic Syndrome X
Heart Diseases
Obesity
Diabetes Mellitus
Dysequilibrium Syndrome

Pathways

Transport
Glucose Transport

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lrguk

References

PMID: 25781171 by Liu Y., et al. LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility.

PMID: 28003339 by Okuda H., et al. LRGUK1 is part of a multiprotein complex required for manchette function and male fertility.