LRIG3 Antibodies

AND LRIG3 ELISA kits, LRIG3 Proteins

Many biological assays use antibodies to detect LRIG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRIG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRIG3 antibodies...

We validate the specificity of these antibodies to LRIG3 by testing them on tissues known to express LRIG3 positively and negatively. Browse below to find the LRIG3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for LRIG3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the LRIG3 Western Blot Guide

LRIG3 Infographic by Boster Bio

All LRIG3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human LRIG3 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK1503
96 wells/kit, with removable strips.

Anti-LRIG3 Antibody Picoband®

Western blot analysis of LRIG3 using anti-LRIG3 antibody (PB10077)

Human, Rat

$370
Cat # PB10077
100 μg/vial

Anti-LRIG3 Antibody (N-Term)

Human

$299
Cat # M10158
50 µl

LRIG3 (NM_153377) Human Over-expression Lysate

Human

$628
Cat # LS121227
20 µg, 100 µg

LRIG3 Overview

Facts about Leucine-rich repeats and immunoglobulin-like domains protein 3.

LRIG3 3D structure. Source: alphafold

Leucine-rich repeats and immunoglobulin-like domains protein 3 (LRIG3)

May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).

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Gene Information

Human
Gene Name:	LRIG3
Uniprot:	Q6UXM1
Entrez:	121227

Family

Belongs to:

No superfamily

Alternative Names

FLJ90440; KIAA3016; leucine-rich repeats and immunoglobulin-like domains 3; leucine-rich repeats and immunoglobulin-like domains protein 3; LIG-3; LIG3FLJ26573; LIRG3; LRIG3

Molecular Weight

Mass (kDA):
123.434 kDA

Genomic Context


Human

Location:	12q14.1
Sequence:	12; NC_000012.12 (58872155..58920519, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Detected in cytoplasmic vesicles when coexpressed with ERBB4.

Diseases

Neoplasms
Brain Neoplasms
Glioma
Malignant Neoplasms
Cell Transformation, Neoplastic
Glioblastoma
Oligodendroglioma
Astrocytoma
Tumor Progression
Neoplasm Invasiveness
Carcinoma
Psoriasis

Crest Syndrome
Circling Gait
Adenoma
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Urinary Bladder
Malignant Tumor Of Cervix

Pathways

Pathogenesis
Localization
Cell Cycle
Cell Proliferation
Gene Silencing
Tissue Morphogenesis
Rna Interference
Inner Ear Morphogenesis
Gastrulation
Aging
Ear Morphogenesis

Receptor Internalization
Axon Guidance
Semicircular Canal Formation
Cell Growth
Neural Crest Formation
Oncogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRIG3

References

PMID: 15203213 by Guo D., et al. The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea.