LRP1B Antibodies

AND LRP1B ELISA kits, LRP1B Proteins

Many biological assays use antibodies to detect LRP1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRP1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRP1B antibodies...

We validate the specificity of these antibodies to LRP1B by testing them on tissues known to express LRP1B positively and negatively. Browse below to find the LRP1B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for LRP1B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LRP1B IHC Guide

LRP1B Infographic by Boster Bio

All LRP1B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LRP1B Antibody

Human, Mouse, Rat

ELISA, IHC

$370
Cat # A07425-1
100 μg/vial

LRP1B Overview

Facts about Low-density lipoprotein receptor-related protein 1B.

Low-density lipoprotein receptor-related protein 1B (LRP1B)

Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis. .

Gene Information

Human
Gene Name:	LRP1B
Uniprot:	Q9NZR2
Entrez:	53353

Family

Belongs to:

LDLR family

Alternative Names

EC 1.1.1.94; EC 3.4.21.9; low density lipoprotein receptor related protein-deleted in tumor; low density lipoprotein receptor-related protein 1B; low density lipoprotein-related protein 1B (deleted in tumors); Low-density lipoprotein receptor-related protein-deleted in tumor; LRP1B; LRP-1B; LRP-deleted in tumors; LRPDIT; LRP-DIT; LRP-DITlow-density lipoprotein receptor-related protein 1B

Molecular Weight

Mass (kDA):
515.498 kDA

Genomic Context


Human

Location:	2q22.1-q22.2
Sequence:	2; NC_000002.12 (140231423..142132463, complement)

Tissue Specificity

Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Alzheimer's Disease
Carcinogenesis
Malignant Neoplasm Of Lung
Carcinoma
Malignant Squamous Cell Neoplasm
Malignant Paraganglionic Neoplasm
Atherosclerosis
Cell Invasion
Obesity
Neoplasm Metastasis

Non-small Cell Lung Carcinoma
Squamous Cell Carcinoma Of Esophagus
Cell Transformation, Neoplastic
Lung Neoplasms
Lymphoma
Rheumatoid Arthritis
Esophageal Neoplasms

Pathways

Endocytosis
Pathogenesis
Methylation
Dna Methylation
Localization
Transport
Receptor-mediated Endocytosis
Aging
Dna Repair
Cellular Response To Dsrna
Cell Migration
Gene Silencing
Proteolysis

Virulence
Glucose Homeostasis
Reverse Transcription
Lipid Homeostasis
Cell Differentiation
Histone Acetylation
Dsrna Fragmentation

PTMs

Phosphorylation
Methylation
Cleavage
Demethylation

Carboxylation
Biotinylation
Reduction
Gamma-carboxylation

Acetylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRP1B

References

PMID: 10766186 by Liu C.-X., et al. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.

PMID: 11031110 by Liu C.-X., et al. Genomic organization of a new candidate tumor suppressor gene, LRP1B.