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- Table of Contents
Facts about Leucine-rich repeat-containing protein 34.
Also critical for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.
| Mouse | |
|---|---|
| Gene Name: | Lrrc34 |
| Uniprot: | Q9DAM1 |
| Entrez: | 71827 |

| Belongs to: |
|---|
| No superfamily |

FLJ27346; leucine rich repeat containing 34; leucine-rich repeat-containing protein 34; MGC27085
Mass (kDA):
46.635 kDA

| Mouse | |
|---|---|
| Location: | 3|3 A3 |
| Sequence: | 3; |
Expressed in testis where it specifically localizes to germ cells (at protein level) (PubMed:24435972, PubMed:24991885). Not detected in other tissues tested (at protein level) (PubMed:24435972, PubMed:24991885). Expressed in pluripotent embryonic stem cells and multipotent adult germline stem cells (PubMed:24991885).


PMID: 24435972 by Chen T., et al. Expression and identification of a novel gene Spata34 in mouse spermatogenic cells.
PMID: 24991885 by Luehrig S., et al. Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells.