LRRK1 Antibodies

AND LRRK1 ELISA kits, LRRK1 Proteins

Many biological assays use antibodies to detect LRRK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRRK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRRK1 antibodies...

We validate the specificity of these antibodies to LRRK1 by testing them on tissues known to express LRRK1 positively and negatively. Browse below to find the LRRK1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LRRK1 Infographic by Boster Bio

All LRRK1 Products

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Anti-LRRK1 Antibody

6 Q&As

Immunofluorescence analysis of HeLa cells, using LRRK1 Antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LRRK1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # A06670
100ul

LRRK1 (NM_024652) Human Over-expression Lysate

Human

$960
Cat # LS079705
20 µg, 100 µg

LRRK1 Overview

Facts about Leucine-rich repeat serine/threonine-protein kinase 1.

LRRK1 3D structure. Source: alphafold

Leucine-rich repeat serine/threonine-protein kinase 1 (LRRK1)

Gene Information

Human
Gene Name:	LRRK1
Uniprot:	Q38SD2
Entrez:	79705

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11.1; FLJ23119; KIAA1790FLJ27465; leucine-rich repeat kinase 1; leucine-rich repeat serine/threonine-protein kinase 1; RIPK6; Roco1

Molecular Weight

Mass (kDA):
225.393 kDA

Genomic Context


Human

Location:	15q26.3
Sequence:	15; NC_000015.10 (100919017..101078257)

Subcellular Localizations

Cytoplasm.

Diseases

Parkinson Disease
Secondary Parkinson Disease
Osteosarcoma
Cell Transformation, Neoplastic
Nerve Degeneration
Neurodegenerative Disorders
Leukemia
Bone Neoplasms

Alzheimer's Disease
Hyperplasia

Interacting Proteins

ABL1
BAG5
CDK5RAP2
DAPK1
EGFR

LRRK2

Pathways

Aging
Pathogenesis
Innervation

PTMs

Phosphorylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRRK1

References

PMID: 16243488 by Korr D., et al. LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain.

PMID: 22952686 by Civiero L., et al. Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers.