LRWD1 Antibodies

AND LRWD1 ELISA kits, LRWD1 Proteins

Many biological assays use antibodies to detect LRWD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRWD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRWD1 antibodies...

We validate the specificity of these antibodies to LRWD1 by testing them on tissues known to express LRWD1 positively and negatively. Browse below to find the LRWD1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LRWD1 Infographic by Boster Bio

All LRWD1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Lrwd1 Antibody

Human, Mouse, Rat

$405
Cat # A06834
100ul

LRWD1 (NM_152892) Human Recombinant Protein

Coomassie blue staining of purified LRWD1 protein

$1249
Cat # PROTQ9UFC0
20 µg

LRWD1 (NM_152892) Human Over-expression Lysate

Human

$628
Cat # LS222229
20 µg, 100 µg

LRWD1 Overview

Facts about Leucine-rich repeat and WD repeat-containing protein 1.

LRWD1 3D structure. Source: alphafold

Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1)

Required for G1/S transition.
Recruits and stabilizes the origin recognition complex (ORC) on chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.

Binds a mixture of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative way with DNA methylation (By similarity).

Gene Information

Mouse
Gene Name:	LRWD1
Uniprot:	Q8BUI3
Entrez:	71735

Family

Belongs to:

LRWD1 family

Alternative Names

DKFZp434K1815; leucine-rich repeats and WD repeat domain containing 1; ORCAleucine-rich repeat and WD repeat-containing protein 1; ORC-associated protein; origin recognition complex associated; Origin recognition complex-associated protein

Molecular Weight

Mass (kDA):
71.594 kDA

Genomic Context


Mouse

Location:	5\|5 G2
Sequence:	5;

Tissue Specificity

Testis-specific.

Pathways

Dna Replication
Methylation
Cell Cycle
Localization
Dna Replication Initiation
Chromatin Organization
Heterochromatin Organization
Mitosis
G1 Phase
Dna Methylation
Regulation Of Gene Expression

Chromosome Segregation
Spermatogenesis
Cell Division
S Phase
Histone Methylation
Chromatin Remodeling

PTMs

Methylation

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRWD1

References

PMID: 17074343 by Lin Y.H., et al. Identification of ten novel genes involved in human spermatogenesis by microarray analysis of testicular tissue.

PMID: 20180869 by Teng Y.N., et al. Expression of lrwd1 in mouse testis and its centrosomal localization.