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- Table of Contents
Leukotriene A-4 hydrolase Antibodies
AND LTA4H ELISA kits, Leukotriene A-4 hydrolase Proteins
Many biological assays use antibodies to detect Leukotriene A-4 hydrolase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Leukotriene A-4 hydrolase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Leukotriene A-4 hydrolase antibodies...
Designing an IHC experiment for Leukotriene A-4 hydrolase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LTA4H IHC GuideLTA4H Infographic by Boster Bio
All LTA4H Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A02399-1
100 µg/vial
Cat # A02399-1
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02399-3
100 μl/vial
Cat # M02399-3
100 μl/vial
Human
$628
Cat # LS004048
20 µg, 100 µg
Cat # LS004048
20 µg, 100 µg
SDS-PAGE
$250
Cat # PROTP09960
Starting from 4ug
Cat # PROTP09960
Starting from 4ug
LTA4H Overview
Facts about Leukotriene A-4 hydrolase.
Leukotriene A-4 hydrolase (LTA4H)
Epoxide hydrolase that catalyzes the last step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | LTA4H |
| Uniprot: | P09960 |
| Entrez: | 4048 |
Family
| Belongs to: |
|---|
| peptidase M1 family |
Alternative Names
EC 3.3.2.6; Leukotriene A(4) hydrolase; Leukotriene A4 Hydrolase; leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4; LTA4H
Molecular Weight
Mass (kDA):
69.285 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.1 |
| Sequence: | 12; NC_000012.12 (96000753..96043520, complement) |
Tissue Specificity
Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts.
Subcellular Localizations
Cytoplasm.
Diseases
- Inflammation
- Asthma
- Malignant Neoplasms
- Infarction
- Neoplasms
- Myocardial Infarction
- Tuberculosis
- Carcinogenesis
- Cerebrovascular Accident
- Arthritis
- Rhinorrhea
- Chronic Obstructive Airway Disease
- Cardiovascular Diseases
Interacting Proteins
- TINF2
Pathways
- Pathogenesis
- Cell Proliferation
- Inflammatory Response
- Chemotaxis
- Transport
- Smooth Muscle Contraction
- Cell Migration
- Monocyte Chemotaxis
- Immune Response
- Dna Methylation
- Muscle Contraction
- Hypersensitivity
- Localization
PTMs
- Cleavage
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTA4H
bosterbio.com/bosterbio-gene-info-cards/LTA4H
References
PMID: 3654641 by Minami M., et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis.
PMID: 2821541 by Funk C.D., et al. Molecular cloning and amino acid sequence of leukotriene A4 hydrolase.