Lymphotoxin-beta Antibodies

AND LTB ELISA kits, Lymphotoxin-beta Proteins

Many biological assays use antibodies to detect Lymphotoxin-beta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphotoxin-beta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphotoxin-beta antibodies...

We validate the specificity of these antibodies to Lymphotoxin-beta by testing them on tissues known to express LTB positively and negatively. Browse below to find the LTB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LTB Infographic by Boster Bio

All LTB Products

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Anti-TNFC LTB Antibody

7 Q&As

Western Blot analysis of various cells using LT-β Polyclonal Antibody

Immunofluorescence analysis of HeLa cells, using TNFC Antibody

Western blot analysis of lysates from HepG2 cells, using TNFC Antibody

Human, Mouse

ELISA, IF, ICC, WB

$335
Cat # A30476
100ul

TNFC Colorimetric Cell-Based ELISA

Western blot analysis of extracts from HepG2 cells

Human, Mouse

ELISA

$480
Cat # EKC1779
1 kit, containing one 96-well plate and all necessary reagents

Anti-LT-Beta (V211) LTB Antibody

Western blot (WB) analysis of LT-β (V211) pAb at 1:500 dilution
Lane1:H9C2 whole cell lysate(40ug)
Lane2:MEF whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate(40ug)
Lane5:HepG2 whole cell lysate(40ug)
Lane6:A549 whole cell lysate(40ug)

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A02565-1
100ul

Anti-Ltb Antibody Picoband®

Western blot analysis of Ltb using anti-Ltb antibody (A02565-2)

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02565-2
100 µg/vial

LTB Overview

Facts about Lymphotoxin-beta.

LTB 3D structure. Source: alphafold

Lymphotoxin-beta (LTB)

Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation.

Gives the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is likely non-functional.

Gene Information

Human
Gene Name:	LTB
Uniprot:	Q06643
Entrez:	4050

Family

Belongs to:

tumor necrosis factor family

Alternative Names

LTB; lymphotoxin beta (TNF superfamily, member 3); Lymphotoxin beta; lymphotoxin-beta; p33; TNFCTNF-C; TNFSF3; TNFSF3LT-beta; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3

Molecular Weight

Mass (kDA):
25.39 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (31580558..31582425, complement)

Tissue Specificity

Spleen and thymus.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Inflammation
Asthma
Edema
Inflammatory Response
Tissue Adhesions
Malignant Neoplasms
Arthritis
Lung Diseases
Chronic Obstructive Airway Disease
Pneumonia
Cholera
Lung Diseases, Obstructive
Neoplasms

Infective Disorder
Inflammatory Bowel Diseases
Allergy
Atherosclerosis
Diarrhea
Rheumatoid Arthritis
Colitis

Pathways

Pathogenesis
Secretion
Chemotaxis
Immune Response
Inflammatory Response
Phagocytosis
Hypersensitivity
Localization
Cytokine Production
Neutrophil Chemotaxis
Neutrophil Activation
Transport
Cell Activation

Cell Growth
Cell Adhesion
Lipoxygenase Pathway
Cell Proliferation
Anaphylaxis
Respiratory Burst
Cell Death

PTMs

Phosphorylation
Hydroxylation
Oxidation
Methylation
Reduction
Ribosylation
Nitration

Cleavage
Acetylation
Formylation
Carboxylation
Acylation
Ubiquitination
Iodination

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTB

References

PMID: 7916655 by Browning J.L., et al. Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface.

PMID: 9299492 by Warzocha K., et al. Identification of two lymphotoxin beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas.