LTBP4 Antibodies

AND LTBP4 ELISA kits, LTBP4 Proteins

Many biological assays use antibodies to detect LTBP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LTBP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LTBP4 antibodies...

We validate the specificity of these antibodies to LTBP4 by testing them on tissues known to express LTBP4 positively and negatively. Browse below to find the LTBP4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LTBP4 Infographic by Boster Bio

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LTBP4 Overview

Facts about Latent-transforming growth factor beta-binding protein 4.

LTBP4 3D structure. Source: alphafold

Latent-transforming growth factor beta-binding protein 4 (LTBP4)

May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play crucial roles in controlling and directing the activity of TGFB1.

May have a structural role in the extracellular matrix (ECM) (By similarity). .

Gene Information

Human
Gene Name:	LTBP4
Uniprot:	Q8N2S1
Entrez:	8425

Family

Belongs to:

LTBP family

Alternative Names

Latent TGFbeta bp4; Latent TGF-beta bp4; latent transforming growth factor beta binding protein 4; LTBP4; LTBP-4; LTBP4L; LTBP4S

Molecular Weight

Mass (kDA):
173.435 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40593166..40629820)

Tissue Specificity

Highly expressed in heart, skeletal muscle, pancreas, uterus, and small intestine. Weakly expressed in placenta and lung.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Paraganglionic Neoplasm
Carcinoma
Aneurysm
Pulmonary Emphysema
Mammary Neoplasms
Carcinogenesis
Colorectal Cancer
Malignant Neoplasm Of Breast
Adenocarcinoma
Aortic Aneurysm
Colorectal Neoplasms

Aortic Aneurysm, Abdominal
Ductal Breast Carcinoma
Lung Diseases
Cutis Laxa
Lung Diseases, Obstructive
Dystrophy
Chronic Obstructive Airway Disease

Interacting Proteins

ATXN7
CACNA1A

Pathways

Secretion
Pathogenesis
Cell Proliferation
Lung Development
Cell Adhesion
Cell Migration
Tissue Morphogenesis
Elastic Fiber Assembly
Proteolysis

Reverse Transcription
Translation
Dedifferentiation
Angiogenesis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTBP4

References

PMID: 9271198 by Giltay R., et al. Sequence and expression of a novel member (LTBP-4) of the family of latent transforming growth factor-beta binding proteins.

PMID: 9660815 by Saharinen J., et al. Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4.