E3 ubiquitin-protein ligase listerin (LTN1)

E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination contributes to VCP/p97 recruiting for extraction and degradation of the incomplete translation product (By similarity).

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