Leucine rich adaptor protein 1 (Lurap1)

Acts as an activator of the canonical NF-kappa-B pathway and induce the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway.

In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is imperative to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, resulting in MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin meeting in the lamella (By similarity).