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- Table of Contents
Lymphocyte antigen 6E Antibodies
AND LY6E ELISA kits, Lymphocyte antigen 6E Proteins
Many biological assays use antibodies to detect Lymphocyte antigen 6E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphocyte antigen 6E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphocyte antigen 6E antibodies...
Designing a Western blot for Lymphocyte antigen 6E? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LY6E Western Blot GuideLY6E Infographic by Boster Bio
All LY6E Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A09496-2
100 μg/vial
Cat # A09496-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M09496
100 μg
Cat # M09496
100 μg
LY6E Overview
Facts about Lymphocyte antigen 6E.
Lymphocyte antigen 6E (LY6E)
Involved in T-cell development.
Believed to serve as a modulator of nicotinic acetylcholine receptors (nAChRs) activity.In vitro inhibits alpha-3:beta-4-containing nAChRs maximum reaction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LY6E |
| Uniprot: | Q16553 |
| Entrez: | 4061 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Ly6E; Ly-6E; lymphocyte antigen 6 complex, locus E; Retinoic acid-induced gene E protein; RIGE; RIGE9804; RIG-Ely-6E; SCA2; SCA2Ly-6E; SCA-2lymphocyte antigen 6E; Stem cell antigen 2; Thymic shared antigen 1; TSA1; TSA-1retinoic acid induced gene E
Molecular Weight
Mass (kDA):
13.507 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q24.3 |
| Sequence: | 8; NC_000008.11 (143018485..143022410) |
Tissue Specificity
Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes.
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor.
Diseases
- Lupus Erythematosus, Systemic
- Neoplasms
- Malignant Neoplasms
- Kidney Diseases
- Rheumatism
- Immunologic Deficiency Syndromes
- Poultry Diseases
- Rheumatoid Arthritis
- T-cell Lymphoma
- Arthritis
- Lung Neoplasms
- Proteinuria Of Undiagnosed Cause
Pathways
- Pathogenesis
- Acrosome Reaction
- Cell Adhesion
- Cell Activation
- Fertilization
- Metaphase
- B Cell Activation
- Localization
- Regulation Of Type I Interferon Production
- Type I Interferon Production
- Disease Resistance
PTMs
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LY6E
bosterbio.com/bosterbio-gene-info-cards/LY6E
References
PMID: 8650192 by Mao M., et al. RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.
PMID: 8757598 by Capone M.C., et al. Identification through bioinformatics of cDNAs encoding human thymic shared Ag-1/stem cell Ag-2: a new member of the human Ly-6 family.