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- Table of Contents
Facts about Lysozyme-like protein 6.
Shows weak bacteriolytic action against Gram-positive bacteria at physiological pH (PubMed:28182716). Bacteriolytic activity is pH- dependent, with a maximum at approximately pH 5.
Human | |
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Gene Name: | LYZL6 |
Uniprot: | O75951 |
Entrez: | 57151 |
Belongs to: |
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glycosyl hydrolase 22 family |
EC 3.2.1.17; LYC1lysozyme homolog; lysozyme-like 6; lysozyme-like protein 6; PRO1485; TKAL754; UNQ754
Mass (kDA):
16.956 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (35934518..35943713, complement) |
Expressed in testis, epididymis and spermatozoa (at protein level) (PubMed:16014814, PubMed:28182716). Expressed in late-stage spermatocytes and round spermatids (PubMed:28182716).
Secreted. Cell surface. Cell projection, cilium, flagellum. Detected on the postacrosomal membrane of mature spermatozoa (PubMed:28182716).
PMID: 10213461 by Nomiyama H., et al. Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES.
PMID: 16014814 by Zhang K., et al. Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family.