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- Table of Contents
Designing an IHC experiment for Lactb? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LACTB IHC GuideFacts about Serine beta-lactamase-like protein LACTB, mitochondrial.
It's unclear whether it functions directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (By similarity). Acts as a tumor suppressor that has the capacity to inhibit proliferation of multiple types of cancer cells: probably by promoting diminished levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758).
| Mouse | |
|---|---|
| Gene Name: | Lactb |
| Uniprot: | Q9EP89 |
| Entrez: | 80907 |

| Belongs to: |
|---|
| peptidase S12 family |

AmpC; EC 3.4; FLJ14902; G24; lactamase, beta; mitochondrial 39S ribosomal protein L56; mitochondrial ribosomal protein L56; MRPL56; serine beta lactamase-like protein LACTB; serine beta-lactamase-like protein LACTB, mitochondrial
Mass (kDA):
60.705 kDA

| Mouse | |
|---|---|
| Location: | 9|9 C |
| Sequence: | 9; |
Expressed predominantly in liver.




PMID: 11707067 by Smith T.S., et al. Identification, genomic organization, and mRNA expression of LACTB, encoding a serine beta-lactamase-like protein with an amino-terminal transmembrane domain.
PMID: 28329758 by Keckesova Z., et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state.