Leiomodin-2 Antibodies

AND Lmod2 ELISA kits, Leiomodin-2 Proteins

Many biological assays use antibodies to detect Leiomodin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Leiomodin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Leiomodin-2 antibodies...

We validate the specificity of these antibodies to Leiomodin-2 by testing them on tissues known to express Lmod2 positively and negatively. Browse below to find the Lmod2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lmod2 Infographic by Boster Bio

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Lmod2 Overview

Facts about Leiomodin-2.

Leiomodin-2 (Lmod2)

Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length (PubMed:26487682).

Required for normal sarcomere organization at the center, and for normal heart function (PubMed:26487682, PubMed:27274810). .

Gene Information

Mouse
Gene Name:	Lmod2
Uniprot:	Q3UHZ5
Entrez:	93677

Family

Belongs to:

tropomodulin family

Alternative Names

C-LMOD; Leiomodin 2 (Cardiac); leiomodin-2; LMOD2

Molecular Weight

Mass (kDA):
62.018 kDA

Genomic Context


Mouse

Location:	6\|6 A3.1
Sequence:	6;

Tissue Specificity

Detected in neonate heart (at protein level) (PubMed:26487682). Detected in embryonic heart and in pharyngeal arches (PubMed:26487682). Detected in adult heart (PubMed:27274810).

Diseases

Mental Disorders
Hypertrophic Cardiomyopathy
Pcp - Hallucinogen-related Disorder
Cardiomyopathies
Hypertrophy
Graves Disease
Schizophrenia

Psychotic Disorders

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lmod2

References

PMID: 11318603 by Conley C.A., et al. Leiomodins: larger members of the tropomodulin (Tmod) gene family.

PMID: 17572376 by Kostyukova A.S.; Leiomodin/tropomyosin interactions are isoform specific.