Leiomodin-3 Antibodies

AND LMOD3 ELISA kits, Leiomodin-3 Proteins

Many biological assays use antibodies to detect Leiomodin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Leiomodin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Leiomodin-3 antibodies...

We validate the specificity of these antibodies to Leiomodin-3 by testing them on tissues known to express LMOD3 positively and negatively. Browse below to find the LMOD3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LMOD3 Infographic by Boster Bio

All LMOD3 Products

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Specificity

Applications

Price

Leiomodin 3 (LMOD3) (NM_198271) Human Recombinant Protein

Coomassie blue staining of purified LMOD3 protein

$1249
Cat # PROTQ0VAK6
20 µg

Leiomodin 3 (LMOD3) (NM_198271) Human Over-expression Lysate

Human

$960
Cat # LS056203
20 µg, 100 µg

Anti-LMOD3 Antibody Picoband®

Western blot analysis of LMOD3 using anti-LMOD3 antibody (A10356-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A10356-2
100 μg/vial

Anti-LMOD3 Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A10356-1
100 μl/vial

LMOD3 Overview

Facts about Leiomodin-3.

LMOD3 3D structure. Source: alphafold

Leiomodin-3 (LMOD3)

Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25250574). Increases the rate of actin polymerization (PubMed:25250574).

Gene Information

Human
Gene Name:	LMOD3
Uniprot:	Q0VAK6
Entrez:	56203

Family

Belongs to:

tropomodulin family

Alternative Names

DKFZp313F0135; leiomodin 3 (fetal); Leiomodin, fetal form; leiomodin-3

Molecular Weight

Mass (kDA):
64.914 kDA

Genomic Context


Human

Location:	3p14.1
Sequence:	3; NC_000003.12 (69106065..69122595, complement)

Tissue Specificity

Expressed in cardiac and at higher levels in skeletal muscles (at protein level).

Subcellular Localizations

Cytoplasm. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, cytoskeleton. Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end.

Diseases

Nemaline myopathy 10 (NEM10)

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMOD3

References

PMID: 25250574 by Yuen M., et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy.