Lymphocyte antigen 6D Antibodies

AND LY6D ELISA kits, Lymphocyte antigen 6D Proteins

Many biological assays use antibodies to detect Lymphocyte antigen 6D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphocyte antigen 6D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphocyte antigen 6D antibodies...

We validate the specificity of these antibodies to Lymphocyte antigen 6D by testing them on tissues known to express LY6D positively and negatively. Browse below to find the LY6D antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Lymphocyte antigen 6D? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LY6D IHC Guide

LY6D Infographic by Boster Bio

All LY6D Products

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Specificity

Applications

Price

Anti-LY6D Antibody Picoband®

Western blot analysis of LY6D using anti-LY6D antibody (A09680)

IHC analysis of LY6D using anti-LY6D antibody (A09680)

Human

ELISA, IHC, WB

$370
Cat # A09680
100 µg/vial

LY6D (NM_003695) Human Over-expression Lysate

Human

$628
Cat # LS008581
20 µg, 100 µg

Human LY6D Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ14210
Starting from 20ug

LY6D Overview

Facts about Lymphocyte antigen 6D.

LY6D 3D structure. Source: alphafold

Lymphocyte antigen 6D (LY6D)

May act as a specification mark at first phase specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification.

Gene Information

Human
Gene Name:	LY6D
Uniprot:	Q14210
Entrez:	8581

Family

Belongs to:

No superfamily

Alternative Names

E48E48 antigen; Ly-6D; lymphocyte antigen 6 complex, locus D; lymphocyte antigen 6D

Molecular Weight

Mass (kDA):
13.286 kDA

Genomic Context


Human

Location:	8q24.3
Sequence:	8; NC_000008.11 (142784882..142786539, complement)

Tissue Specificity

Expressed exclusively at the outer cell surface of transitional epithelia and the keratinocyte of stratified squamous epithelia.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Malignant Squamous Cell Neoplasm
Head And Neck Neoplasms
Neoplasm Metastasis
Malignant Neck Neoplasm
Malignant Head And Neck Neoplasm
Head And Neck Carcinoma
Malignant Paraganglionic Neoplasm
Tumor Progression
Metastatic Malignant Neoplasm To The Lymph Node
Neoplasm, Residual

Ovarian Neoplasm
Adenocarcinoma
Colorectal Neoplasms
Tissue Adhesions
Lymphatic Metastasis
Adenoma
Neoplasms, Experimental

Pathways

Cell Activation
Cell Proliferation
Cell-cell Recognition
Proteolysis
Glycosylation
Angiogenesis
Cell Recognition

Cell-cell Adhesion

PTMs

Glycosylation

Reduction

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LY6D

References

PMID: 7790363 by Brakenhoff R.H., et al. The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.

PMID: 9366413 by Brakenhoff R.H., et al. A gain of novel tissue specificity in the human Ly-6 gene E48.