Protein mab-21-like 2 Antibodies

AND MAB21L2 ELISA kits, Protein mab-21-like 2 Proteins

Many biological assays use antibodies to detect Protein mab-21-like 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein mab-21-like 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein mab-21-like 2 antibodies...

We validate the specificity of these antibodies to Protein mab-21-like 2 by testing them on tissues known to express MAB21L2 positively and negatively. Browse below to find the MAB21L2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAB21L2 Infographic by Boster Bio

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MAB21L2 (NM_006439) Human Over-expression Lysate

Human

$628
Cat # LS010586
20 µg, 100 µg

MAB21L2 Overview

Facts about Protein mab-21-like 2.

MAB21L2 3D structure. Source: alphafold

Protein mab-21-like 2 (MAB21L2)

Required for many aspects of embryonic development including normal evolution of the eye. .

Gene Information

Human
Gene Name:	MAB21L2
Uniprot:	Q9Y586
Entrez:	10586

Family

Belongs to:

mab-21 family

Alternative Names

FLJ31103; mab-21 (C. elegans)-like 2; mab-21-like 2 (C. elegans); protein mab-21-like 2

Molecular Weight

Mass (kDA):
40.923 kDA

Genomic Context


Human

Location:	4q31.3
Sequence:	4; NC_000004.12 (150582151..150584693)

Subcellular Localizations

Nucleus. Cytoplasm. Predominantly localizes to the nucleus, with some cytoplasmic localization (PubMed:25719200).

Diseases

Adenoma
Microphthalmos
Overlying Behavior
Degenerative Polyarthritis
Carcinoma
Neoplasms
Nervousness
Chimera Disorder
Osteoporosis
Colorectal Cancer
Cytogenetic Abnormality
Rheumatoid Arthritis

Embryonic Mosaic
Aphakia
Cell Transformation, Neoplastic
Chromosomal Duplication
Intestinal Neoplasms
Haploinsufficiency

Interacting Proteins

CCDC102B
GOLGA2
KRT40
PNMA1

Pathways

Gastrulation
Somitogenesis
Eye Morphogenesis
Eye Development
Cell Proliferation
Fertilization
Aging
Brain Development
Tube Formation
Vasculogenesis
Liver Development
Localization
Regeneration

Reverse Transcription
Translation
Cell Death
Forebrain Development
Neural Tube Formation
Regionalization
Pathogenesis

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAB21L2

References

PMID: 10556287 by Mariani M., et al. Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.

PMID: 24906020 by Rainger J., et al. Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.