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MACC1 Antibodies

AND MACC1 ELISA kits, MACC1 Proteins

Many biological assays use antibodies to detect MACC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MACC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MACC1 antibodies...

We validate the specificity of these antibodies to MACC1 by testing them on tissues known to express MACC1 positively and negatively. Browse below to find the MACC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MACC1 Infographic by Boster Bio

MACC1 protein infographic

All MACC1 Products

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Figures

Specificity

Applications

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Anti-MACC1 Antibody

Western blot analysis of MACC1 in mouse liver tissue lysate with MACC1 antibody at (A) 1 and (B) 2 μg/mL

Western blot analysis of MACC1 in mouse liver tissue lysate with MACC1 antibody at (A) 1 and (B) 2 μg/mL

Immunofluorescence of MACC1 in Human Liver cells with MACC1 antibody at 20 μg/mL

Immunohistochemistry of MACC1 in human liver tissue with MACC1 antibody at 2

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A04732
0.1 mg

MACC1 (NM_182762) Human Over-expression Lysate

MACC1 Human Over-expression Lysates NM_182762

MACC1 Human Over-expression Lysates NM_182762

Human

$960
Cat # LS346389
20 µg, 100 µg

MACC1 Overview

Facts about Metastasis-associated in colon cancer protein 1.

MACC1 3D structure

MACC1 3D structure. Source: alphafold

Metastasis-associated in colon cancer protein 1 (MACC1)

Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling.
Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.

.

Gene Information

Human
Gene Name:	MACC1
Uniprot:	Q6ZN28
Entrez:	346389

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

metastasis associated in colon cancer 1; SH3 domain-containing protein 7a5,7A5

Molecular Weight

Mass (kDA):
96.639 kDA

Molecular Weight

Genomic Context


Human

Location:	7p21.1
Sequence:	7; NC_000007.14 (20134655..20217384, complement)

Tissue Specificity

Preferentially expressed in metastasizing tumors.

Subcellular Localizations

Cytoplasm. Nucleus. Mainly found in the cytoplasm in non-metastasizing tumors.

Subcellular Localization

Diseases

Malignant Neoplasms
Neoplasm Metastasis
Neoplasms
Malignant Tumor Of Colon
Colorectal Cancer
Cell Invasion
Carcinoma
Colorectal Neoplasms
Colonic Neoplasms
Adenocarcinoma
Neoplasm Recurrence, Local
Liver Carcinoma

Metastatic Malignant Neoplasm To The Lymph Node
Neoplasm Invasiveness
Malignant Paraganglionic Neoplasm
Liver Neoplasms
Lung Neoplasms
Lymphatic Metastasis
Metastatic Malignant Neoplasm To The Liver

Disease

Pathways

Cell Motility
Bioluminescence
Drug Resistance
Reverse Transcription
Cell Proliferation
Cell Migration
Cell Growth
Invasive Growth
Angiogenesis

Wound Healing
Rna Interference
Localization

Pathways

PTMs

Cleavage

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MACC1

References

PMID: 19098908 by Stein U., et al. MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.