Transcription factor MafB Antibodies

AND MAFB ELISA kits, Transcription factor MafB Proteins

Many biological assays use antibodies to detect Transcription factor MafB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor MafB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor MafB antibodies...

We validate the specificity of these antibodies to Transcription factor MafB by testing them on tissues known to express MAFB positively and negatively. Browse below to find the MAFB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAFB Infographic by Boster Bio

All MAFB Products

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Specificity

Applications

Price

Anti-Transcription factor MafB MAFB Antibody

Human, Mouse, Rat

$405
Cat # A02446
100ul

Anti-MAFB Mouse Monoclonal Antibody [Clone ID: OTI1E9]

+14

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M02446
100 µl

MAFB (NM_005461) Human Over-expression Lysate

Human

$628
Cat # LS009935
100 µg

MAFB Overview

Facts about Transcription factor MafB.

MAFB 3D structure. Source: alphafold

Transcription factor MafB (MAFB)

Plays a pivotal role in regulating lineage- specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation.

Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters.

Gene Information

Human
Gene Name:	MAFB
Uniprot:	Q9Y5Q3
Entrez:	9935

Family

Belongs to:

bZIP family

Alternative Names

Kreisler (mouse) maf-related leucine zipper homolog; Kreisler maf-related leucine zipper homolog; KRML; KRMLMAFB/Kreisler basic region/leucine zipper transcription factor; MafB; Maf-B; MGC43127; transcription factor MafB; v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

Molecular Weight

Mass (kDA):
35.792 kDA

Genomic Context


Human

Location:	20q12
Sequence:	20; NC_000020.11 (40685848..40689236, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Multiple Myeloma
Chromosomal Translocation
Neoplasms
Leukemia
Malignant Neoplasms
Crest Syndrome
Fibrosarcoma
Cleft Palate
Cleft Lip
Monoclonal Gammopathy Of Undetermined Significance
Malignant Paraganglionic Neoplasm
Leukemia, Plasma Cell

Cell Transformation, Neoplastic
Monoclonal Gammapathies
Dysplasia
Myeloid Leukemia
Diabetes Mellitus
Trisomy

Interacting Proteins

BACH1
IRF3
MAF

Pathways

Segmentation
Pathogenesis
Hindbrain Development
Cell Differentiation
Macrophage Differentiation
Secretion
Osteoclast Differentiation
Translation
Insulin Secretion
Cell Cycle
Regeneration
Cell Development
Localization

Methylation
Cell Adhesion
Cell Maturation
Interphase
Ear Development
Cellular Localization
Gene Silencing

PTMs

Methylation
Phosphorylation

Cleavage
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAFB

References

PMID: 10444328 by Wang P.W., et al. Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias.

PMID: 15135046 by Petersen H.H., et al. Low-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain development.