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- Table of Contents
MALT1 Antibodies
AND MALT1 ELISA kits, MALT1 Proteins
Many biological assays use antibodies to detect MALT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MALT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MALT1 antibodies...
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MALT1 Infographic by Boster Bio
All MALT1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1920
100 μg/vial
Cat # PA1920
100 μg/vial
MALT1 Overview
Facts about Mucosa-associated lymphoid tissue lymphoma translocation protein 1.
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1)
Enhances BCL10-induced activation of NF-kappa-B.
Involved in nuclear export of BCL10.Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | MALT1 |
| Uniprot: | Q9UDY8 |
| Entrez: | 10892 |
Family
| Belongs to: |
|---|
| peptidase C14B family |
Alternative Names
caspase-like protein; DKFZp434L132; EC 3.4.22.-; MALT associated translocation; MALT lymphoma-associated translocation; MALT1; MLT1; MLTMALT-lymphoma associated translocation; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase
Molecular Weight
Mass (kDA):
92.272 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q21.32 |
| Sequence: | 18; NC_000018.10 (58671420..58754477) |
Tissue Specificity
Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
Subcellular Localizations
Cytoplasm, perinuclear region. Nucleus. Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
Diseases
- Lymphoma
- Mucosa-associated Lymphoid Tissue Lymphoma
- Marginal Zone B-cell Lymphoma
- B-cell Lymphomas
- Chromosomal Translocation
- T(11;18)(q21;q21)
- Neoplasms
- Cytogenetic Abnormality
- Diffuse Large B-cell Lymphoma
- Malignant Neoplasms
- Stomach Neoplasms
Interacting Proteins
- BCL10
- CARD11
- CASP8
- CSNK1A1
- IKBKG
- SHARPIN
- SQSTM1
- TRAF6
- UBC
Pathways
- Pathogenesis
- Interphase
- Cell Activation
- Lymphocyte Activation
- Cytokine Production
- Immune Response
- T Cell Activation
- Cell Proliferation
- Adaptive Immune Response
- Localization
- Secretion
- Methylation
- Rna Interference
PTMs
- Phosphorylation
- Cleavage
- Ubiquitination
- Methylation
Research Areas
- Apoptosis
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MALT1
bosterbio.com/bosterbio-gene-info-cards/MALT1
References
PMID: 10339464 by Dierlamm J., et al. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.
PMID: 10523859 by Akagi T., et al. A novel gene, MALT1 at 18q21, is involved in t(11;18)(q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue.