Microtubule-associated proteins 1A/1B light chain 3 beta 2 (MAP1LC3B2)

Ubiquitin-like modifier involved in creation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to meet cellular energy requirements and preventing excess ROS production.

Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). .