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MAP2K2 Antibodies
AND MAP2K2 ELISA kits, MAP2K2 Proteins
Many biological assays use antibodies to detect MAP2K2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP2K2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP2K2 antibodies...
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MAP2K2 Infographic by Boster Bio
All MAP2K2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00996
100 μl
Cat # M00996
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1362
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1362
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2459
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2459
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00996-2
100 μg/vial
Cat # A00996-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00996-2
100 μg/vial
Cat # M00996-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00996-3
100 μg/vial
Cat # M00996-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00996-3
100 μg/vial
Cat # A00996-3
100 μg/vial
MAP2K2 Overview
Facts about Dual specificity mitogen-activated protein kinase kinase 2.
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2)
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MAP2K2 |
| Uniprot: | P36507 |
| Entrez: | 5605 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
ERK activator kinase 2; MAP2K2; MAPKK 2; MEK 2; MEK2; MEK2EC 2.7.12.2; mitogen-activated protein kinase kinase 2; MKK2; MKK2FLJ26075; p45; PRKMK2MAPKK2
Molecular Weight
Mass (kDA):
44.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (4090321..4124184, complement) |
Subcellular Localizations
Cytoplasm. Membrane; Peripheral membrane protein. Membrane localization is probably regulated by its interaction with KSR1.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Cardio-facio-cutaneous Syndrome
- Cell Transformation, Neoplastic
- Congenital Heart Defects
- Melanoma
- Neoplasm Metastasis
- Cell Invasion
- Inflammation
- Mammary Neoplasms
- Leukemia
Interacting Proteins
- ARAF
- BRAF
- CCNDBP1
- DLG1
- KSR1
- RAF1
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Death
- Cell Growth
- Pathogenesis
- Secretion
- Cell Cycle Arrest
- Angiogenesis
- Localization
- Senescence
- Rna Interference
- Cell Migration
- Transport
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Ubiquitination
Research Areas
- Angiogenesis
- Autophagy
- Cancer
- MAP Kinase Signaling
- Phospho-Specific
- Protein Kinase
- Protein Phosphatase
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP2K2
bosterbio.com/bosterbio-gene-info-cards/MAP2K2
References
PMID: 8388392 by Zheng C.-F., et al. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
PMID: 17116858 by Mittal R., et al. Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling.