MAP4K3 Antibodies

AND MAP4K3 ELISA kits, MAP4K3 Proteins

Many biological assays use antibodies to detect MAP4K3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP4K3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP4K3 antibodies...

We validate the specificity of these antibodies to MAP4K3 by testing them on tissues known to express MAP4K3 positively and negatively. Browse below to find the MAP4K3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAP4K3 Infographic by Boster Bio

All MAP4K3 Products

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Product

Figures

Specificity

Applications

Price

Anti-GLK MAP4K3 Antibody

Western blot analysis of extracts of various cell lines, using MAP4K3 antibody

Immunohistochemistry of paraffin-embedded human liver damage using MAP4K3 antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07188-1
100ul

MAP4K3 (NM_003618) Human Over-expression Lysate

Human

$960
Cat # LS008491
20 µg, 100 µg

Anti-MAP4K3 Antibody Picoband®

Western blot analysis of MAP4K3 using anti-MAP4K3 antibody (A07188-2)

IHC analysis of MAP4K3 using anti-MAP4K3 antibody (A07188-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A07188-2
100 µg/vial

MAP4K3 Overview

Facts about Mitogen-activated protein kinase kinase kinase kinase 3.

MAP4K3 3D structure. Source: alphafold

Mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3)

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Gene Information

Human
Gene Name:	MAP4K3
Uniprot:	Q8IVH8
Entrez:	8491

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.1; germinal center kinase-like kinase; Germinal center kinase-related protein kinase; GLKMEKKK 3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Molecular Weight

Mass (kDA):
101.316 kDA

Genomic Context


Human

Location:	2p22.1
Sequence:	2; NC_000002.12 (39248941..39437312, complement)

Tissue Specificity

Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.

Diseases

Malignant Neoplasms
Neoplasms
Lupus Erythematosus, Systemic
Malignant Neoplasm Of Pancreas
Autoimmunity
Sclerosis
Adenocarcinoma
Cell Transformation, Neoplastic
Tumor Progression
Muscular Atrophy
Encephalomyelitis
Experimental Autoimmune Encephalomyelitis

Adult-onset Still Disease
Autoimmune Reaction
Obesity
Pancreatic Neoplasm
Inflammation
Tuberous Sclerosis
Juvenile-onset Still Disease

Interacting Proteins

GRB2
LCP2
PRKCQ
Prkcq

Pathways

Cell Growth
Translation
Transport
Cell Death
Regulation Of Amino Acid Transport
Clathrin-mediated Endocytosis
Response To Stress
Cell Proliferation
Intracellular Signal Transduction
Endocytosis
Amino Acid Homeostasis
Energy Homeostasis
Ribosome Biogenesis

Amino Acid Transport
Cell Cycle
Regulation Of Cell Growth
Pathogenesis
Myoblast Differentiation
Rna Interference
Autophagy

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Lipid and Metabolism
Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP4K3

References

PMID: 9275185 by Diener K., et al. Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase.