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- Table of Contents
Facts about Mitogen-activated protein kinase 13.
Accordingly, p38 MAPKs phosphorylate a wide assortment of proteins and it has been estimated that they might have roughly 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms.
Human | |
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Gene Name: | MAPK13 |
Uniprot: | O15264 |
Entrez: | 5603 |
Belongs to: |
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protein kinase superfamily |
EC 2.7.11; EC 2.7.11.24; MAP kinase 13; MAPK 13; MAPK13; MGC99536; mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta; p38delta; PRKM13; SAPK4MAP kinase p38 delta; Stress-activated protein kinase 4
Mass (kDA):
42.09 kDA
Human | |
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Location: | 6p21.31 |
Sequence: | 6; NC_000006.12 (36130513..36144521) |
Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells.
Boster is the right company to contact if you need primary antibodies. Boster produces antibodies with high affinity that have been validated on immunohistochemistry, Western Blotting, and ELISA. Boster is trusted by researchers because the antibodies are of high quality. This article will give you a brief introduction to Steven Boster's research. Below are some of our most useful antibodies for MAPK13 research.
The functional characterization of the MAPK13 marker reveals that it promotes cell migration and invasion, and thus may play a vital role in metastasis of CCA. The MAPK13 protein could be a key target for cancer research. However, further research is needed to determine the precise role of this protein. Here are some key findings based on His research about the MAPK13 marker. Continue reading for more information.
PMID: 9218798 by Goedert M., et al. Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.
PMID: 9374491 by Jiang Y., et al. Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta.