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Macrophage receptor MARCO Antibodies
AND MARCO ELISA kits, Macrophage receptor MARCO Proteins
Many biological assays use antibodies to detect Macrophage receptor MARCO, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Macrophage receptor MARCO in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Macrophage receptor MARCO antibodies...
Designing a Western blot for Macrophage receptor MARCO? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MARCO Western Blot GuideMARCO Infographic by Boster Bio
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MARCO Overview
Facts about Macrophage receptor MARCO.
Macrophage receptor MARCO (MARCO)
Pattern recognition receptor (PRR) which binds Gram- positive and Gram-negative germs (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity).
Binds to the secretoglobin SCGB3A2 (PubMed:12847263). .
Gene Information
| Human | |
|---|---|
| Gene Name: | MARCO |
| Uniprot: | Q9UEW3 |
| Entrez: | 8685 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
macrophage receptor with collagenous structureSCARA2Scavenger receptor class A member 2; MARCO; member 2; SCARA2
Molecular Weight
Mass (kDA):
52.658 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.2 |
| Sequence: | 2; NC_000002.12 (118942169..118994664) |
Tissue Specificity
Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen (PubMed:9468508).
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein.
Diseases
- Inflammation
- Pneumonia
- Bacterial Infections
- Infective Disorder
- Tissue Adhesions
- Neoplasms
- Lung Diseases
- Fibrosis
- Autoimmune Reaction
- Inflammatory Response
- Autoimmune Diseases
- Atherosclerosis
- Alzheimer's Disease
Pathways
- Phagocytosis
- Pathogenesis
- Immune Response
- Inflammatory Response
- Secretion
- Cell Activation
- Endocytosis
- Cytokine Production
- Cell Death
- Cell Adhesion
- Cell Migration
- Innate Immune Response
- Localization
PTMs
- Phosphorylation
- Acetylation
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCO
bosterbio.com/bosterbio-gene-info-cards/MARCO
References
PMID: 9468508 by Elomaa O., et al. Structure of the human macrophage MARCO receptor and characterization of its bacteria-binding region.
PMID: 10331948 by Kangas M., et al. Structure and chromosomal localization of the human and murine genes for the macrophage MARCO receptor.