MAT1A Antibodies

AND MAT1A ELISA kits, MAT1A Proteins

Many biological assays use antibodies to detect MAT1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAT1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAT1A antibodies...

We validate the specificity of these antibodies to MAT1A by testing them on tissues known to express MAT1A positively and negatively. Browse below to find the MAT1A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAT1A Infographic by Boster Bio

All MAT1A Products

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Specificity

Applications

Price

Anti-MAT1A Antibody

Western blot analysis of extracts of various cell lines, using MAT1A antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A04203
100ul

Human MAT1A Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ00266
Starting from 10ug

Anti-MAT1A Antibody Picoband®

Western blot analysis of MAT1A using anti-MAT1A antibody (A04203-1)

IF analysis of MAT1A using anti-MAT1A antibody (A04203-1) and anti-Alpha Tubulin antibody (M03989-3)

Flow Cytometry analysis of Jurkat cells using anti-MAT1A antibody (A04203-1)

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A04203-1
100 μg/vial

MAT1A (NM_000429) Human Over-expression Lysate

Human

$628
Cat # LS004143
20 µg, 100 µg

MAT1A Overview

Facts about S-adenosylmethionine synthase isoform type-1.

MAT1A 3D structure. Source: alphafold

S-adenosylmethionine synthase isoform type-1 (MAT1A)

Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
The response comprises two steps which are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Gene Information

Human
Gene Name:	MAT1A
Uniprot:	Q00266
Entrez:	4143

Family

Belongs to:

AdoMet synthase family

Alternative Names

AdoMet synthase 1; adoMet synthetase 1; AMS1; MAT; MATA1MAT 1; MAT-I/III; Methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthetase isoform type-1; SAMS; SAMS1EC 2.5.1.6

Molecular Weight

Mass (kDA):
43.648 kDA

Genomic Context


Human

Location:	10q22.3
Sequence:	10; NC_000010.11 (80271820..80289658, complement)

Tissue Specificity

Expressed in liver.

Diseases

Liver Carcinoma
Carcinoma
Liver Neoplasms
Malignant Neoplasms
Liver Diseases
Malignant Neoplasm Of Liver
Injury To Liver
Hepatic Methionine Adenosyltransferase Deficiency
Neoplasms
Steatohepatitis
Cell Transformation, Neoplastic
Liver Cirrhosis
Hepatocarcinogenesis

Liver Regeneration Disorder
Malignant Paraganglionic Neoplasm
Liver Damage
5,10-methylenetetrahydrofolate Reductase Deficiency
Hepatitis
Homocystinuria
Fibrosis

Interacting Proteins

MAT2A

Pathways

Methylation
Cell Growth
Dna Methylation
Regeneration
Cell Proliferation
Liver Regeneration
Dedifferentiation
Pathogenesis
Histone Acetylation
Transport
Dna Hypomethylation
Transsulfuration
Cell Death

Myelination
Aging
Hepatocyte Proliferation
Translation
Mrna Stabilization
Rna Interference
Cell Migration

PTMs

Methylation
Phosphorylation
Acetylation
Deacetylation

Sumoylation
Demethylation
Reduction
Cleavage

Oxidation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAT1A

References

PMID: 8393662 by Alvarez L., et al. Characterization of a full-length cDNA encoding human liver S- adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies.

PMID: 1772450 by Horikawa S., et al. Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase.