MAT2A Antibodies

AND MAT2A ELISA kits, MAT2A Proteins

Many biological assays use antibodies to detect MAT2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAT2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAT2A antibodies...

We validate the specificity of these antibodies to MAT2A by testing them on tissues known to express MAT2A positively and negatively. Browse below to find the MAT2A antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for MAT2A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MAT2A IHC Guide

MAT2A Infographic by Boster Bio

All MAT2A Products

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Anti-MAT2A Antibody Picoband®

2 Citations

Western blot analysis of MAT2A using anti-MAT2A antibody (A04557-1)

IHC analysis of MAT2A using anti-MAT2A antibody (A04557-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A04557-1
100 μg/vial

Anti-Zebrafish MAT2Aa/b Antibody Picoband®

Western blot analysis of MAT2Aa/b using anti-MAT2Aa/b antibody (AZF1QYU7)

IHC analysis of MAT2Aa/b using anti-MAT2Aa/b antibody (AZF1QYU7)

Zebrafish

IHC, WB

$470
Cat # AZF1QYU7
100 μg/vial

Anti-MAT2A Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:8K dilution for 1 hour at room temperature

Western blot analysis of MAT2A expression in (1) Ramos cell lysate;(2) Mouse spleen lysate

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M04557
100 μl/vial

MAT2A (NM_005911) Human Over-expression Lysate

Human

$628
Cat # LS004144
20 µg, 100 µg

Human MAT2A Recombinant Protein

SDS-PAGE

$250
Cat # PROTP31153
Starting from 20ug

MAT2A Overview

Facts about S-adenosylmethionine synthase isoform type-2.

MAT2A 3D structure. Source: alphafold

S-adenosylmethionine synthase isoform type-2 (MAT2A)

Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Gene Information

Human
Gene Name:	MAT2A
Uniprot:	P31153
Entrez:	4144

Family

Belongs to:

AdoMet synthase family

Alternative Names

AdoMet synthase 2; AMS2; EC 2.5.1.6; MAT 2; MATA2SAMS2adoMet synthetase 2; MATII; MAT-II; Methionine adenosyltransferase 2; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2

Molecular Weight

Mass (kDA):
43.661 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (85539168..85545281)

Tissue Specificity

Detected in kidney.

Diseases

Malignant Neoplasms
Liver Carcinoma
Liver Neoplasms
Carcinoma
Malignant Neoplasm Of Liver
Malignant Paraganglionic Neoplasm
Injury To Liver
Liver Regeneration Disorder
Neoplasms
Liver Diseases
Cell Transformation, Neoplastic
Steatohepatitis

5,10-methylenetetrahydrofolate Reductase Deficiency
Anaplasia
Hepatocarcinogenesis
Liver Cirrhosis, Experimental
Obesity
Malignant Tumor Of Colon
Fibrosis

Interacting Proteins

MAT1A
MAT2B

Pathways

Methylation
Dna Methylation
Cell Growth
Regeneration
Liver Regeneration
Dna Hypomethylation
Histone Acetylation
Cell Proliferation
Dedifferentiation
Cell Cycle
Chromatin Remodeling
Transsulfuration
Cell Death

Rna Interference
Transport
Mrna Stabilization
Cell Differentiation
Oncogenesis
Demethylation
Pathogenesis

PTMs

Methylation
Acetylation
Cleavage
Demethylation

Deacetylation
Phosphorylation
Reduction
Ubiquitination

Research Areas

Amino Acids, Drugs and other small molecules
Cancer
Lipid and Metabolism
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAT2A

References

PMID: 1426236 by Horikawa S., et al. Molecular cloning and developmental expression of a human kidney S- adenosylmethionine synthetase.

PMID: 16413417 by Panayiotidis M.I., et al. Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.