MBD5 Antibodies

AND MBD5 ELISA kits, MBD5 Proteins

Many biological assays use antibodies to detect MBD5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MBD5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MBD5 antibodies...

We validate the specificity of these antibodies to MBD5 by testing them on tissues known to express MBD5 positively and negatively. Browse below to find the MBD5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MBD5 Infographic by Boster Bio

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MBD5 Overview

Facts about Methyl-CpG-binding domain protein 5.

MBD5 3D structure. Source: alphafold

Methyl-CpG-binding domain protein 5 (MBD5)

Binds to heterochromatin.
Doesn't interact with either methylated or unmethylated DNA (in vitro).

Gene Information

Human
Gene Name:	MBD5
Uniprot:	Q9P267
Entrez:	55777

Family

Belongs to:

No superfamily

Alternative Names

KIAA1461; methyl-CpG binding domain protein 5; methyl-CpG-binding domain protein 5; methyl-CpG-binding protein MBD5; MRD1

Molecular Weight

Mass (kDA):
159.895 kDA

Genomic Context


Human

Location:	2q23.1
Sequence:	2; NC_000002.12 (148021011..148516971)

Tissue Specificity

Detected in heart, placenta, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

[Isoform 1]: Nucleus. Chromosome. Associated with pericentric heterochromatin.; [Isoform 2]: Nucleus. Not associated with pericentric heterochromatin.

Diseases

Metabolic Bone Disorder
Microcephaly
Haploinsufficiency
Epilepsy
Developmental Delay (disorder)
Developmental Disabilities
Ataxia
Autistic Disorder
Dwarfism
Nervousness
Rett Syndrome

Uniparental Disomy
Brachycephaly
Clinodactyly
Orbital Separation Excessive
Cytogenetic Abnormality
Speech Disorders

Pathways

Dna Methylation
Methylation
Localization
Transport
Fertilization
Brain Development
Mitosis
Metaphase
Glucose Homeostasis
Cell Division

Cellular Localization
Cognition
Nucleocytoplasmic Transport
Chromatin Remodeling

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MBD5

References

PMID: 17847001 by Wagenstaller J., et al. Copy-number variations measured by single-nucleotide-polymorphism oligonucleotide arrays in patients with mental retardation.

PMID: 12529184 by Roloff T.C., et al. Comparative study of methyl-CpG-binding domain proteins.