MCUB Antibodies

AND MCUB ELISA kits, MCUB Proteins

Many biological assays use antibodies to detect MCUB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MCUB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MCUB antibodies...

We validate the specificity of these antibodies to MCUB by testing them on tissues known to express MCUB positively and negatively. Browse below to find the MCUB antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MCUB Infographic by Boster Bio

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CCDC109B (MCUB) (NM_017918) Human Over-expression Lysate

Human

$628
Cat # LS055013
20 µg, 100 µg

MCUB Overview

Facts about Calcium uniporter regulatory subunit MCUb, mitochondrial.

MCUB 3D structure. Source: alphafold

Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB)

Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Doesn't form functional calcium channels alone.

Mitochondrial calcium homeostasis plays crucial roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. .

Gene Information

Human
Gene Name:	MCUB
Uniprot:	Q9NWR8
Entrez:	55013

Family

Belongs to:

MCU (TC 1.A.77) family

Alternative Names

Calcium uniporter regulatory subunit MCUb, mitochondrial

Molecular Weight

Mass (kDA):
39.082 kDA

Genomic Context


Human

Location:	4q25
Sequence:	4; NC_000004.12 (109560246..109688719)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MCUB

References

PMID: 24231807 by Sancak Y., et al. EMRE is an essential component of the mitochondrial calcium uniporter complex.