MED12L Antibodies

AND MED12L ELISA kits, MED12L Proteins

Many biological assays use antibodies to detect MED12L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MED12L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MED12L antibodies...

We validate the specificity of these antibodies to MED12L by testing them on tissues known to express MED12L positively and negatively. Browse below to find the MED12L antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MED12L Infographic by Boster Bio

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MED12L Overview

Facts about Mediator of RNA polymerase II transcription subunit 12-like protein.

MED12L 3D structure. Source: alphafold

Mediator of RNA polymerase II transcription subunit 12-like protein (MED12L)

May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.

Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). .

Gene Information

Human
Gene Name:	MED12L
Uniprot:	Q86YW9
Entrez:	116931

Family

Belongs to:

Mediator complex subunit 12 family

Alternative Names

Mediator of RNA polymerase II transcription subunit 12-like protein

Molecular Weight

Mass (kDA):
240.12 kDA

Genomic Context


Human

Location:	3q25.1
Sequence:	3; NC_000003.12 (151085665..151436677)

Subcellular Localizations

Nucleus.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MED12L

References

PMID: 11524702 by Joensuu T., et al. Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3.

PMID: 11483580 by Yu Y., et al. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.