MEGF11 Antibodies

AND MEGF11 ELISA kits, MEGF11 Proteins

Many biological assays use antibodies to detect MEGF11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MEGF11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MEGF11 antibodies...

We validate the specificity of these antibodies to MEGF11 by testing them on tissues known to express MEGF11 positively and negatively. Browse below to find the MEGF11 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MEGF11 Infographic by Boster Bio

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MEGF11 Overview

Facts about Multiple epidermal growth factor-like domains protein 11.

MEGF11 3D structure. Source: alphafold

Multiple epidermal growth factor-like domains protein 11 (MEGF11)

May regulate the mosaic spacing of particular neuron subtypes in the retina via homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly through the retina, ensuring that all sections of the visual area have access to a full set of processing elements (By similarity).

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Gene Information

Human
Gene Name:	MEGF11
Uniprot:	A6BM72
Entrez:	84465

Family

Belongs to:

MEGF family

Alternative Names

DKFZp434L121; KIAA1781; multiple EGF-like domains protein 11; multiple EGF-like-domains 11; multiple epidermal growth factor-like domains protein 11

Molecular Weight

Mass (kDA):
110.844 kDA

Genomic Context


Human

Location:	15q22.31
Sequence:	15; NC_000015.10 (65889717..66253737, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10.

Diseases

Nervousness

Pathways

Notch Signaling Pathway

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MEGF11

References

PMID: 17498693 by Suzuki E., et al. The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern.