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- Table of Contents
Facts about Meiosis-specific kinetochore protein.
Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of this shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores.
Mouse | |
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Gene Name: | Meikin |
Uniprot: | Q5F2C3 |
Entrez: | 74847 |
Belongs to: |
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No superfamily |
Meiosis-specific kinetochore protein
Mass (kDA):
47.423 kDA
Mouse | |
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Location: | 11|11 B1.3 |
Sequence: | 11; |
Germ cell-specific. Expressed in both testis and ovary. Not expressed in other tissues.
PMID: 25533956 by Kim J., et al. Meikin is a conserved regulator of meiosis-I-specific kinetochore function.